I began my scientific journey studying Biochemistry at Imperial College London, where I graduated with first-class honours. My early research experiences sparked my interest in metabolism and its intricate regulatory mechanisms, leading me to pursue a PhD in Professor Julian Griffin’s group at the University of Cambridge. During my PhD, I explored how specific amino acids influence insulin resistance via de novo lipogenesis, mastering advanced metabolomic, lipidomic, and bioinformatic techniques. While I always knew I wanted to stay in science, it was during my final year of PhD research that I became particularly fascinated by the interplay between metabolism and epigenetics. At the time, the field of metabolism was rapidly evolving, with growing recognition of its connection to epigenetic regulation.

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My research focuses on the intricate relationship between metabolism and epigenetics, exploring how these two fundamental processes influence human health and disease. By integrating cutting-edge metabolomics, epigenomics, and proteomics approaches, my team investigates how epigenetic modifications regulate metabolic pathways and contribute to disease progression, particularly in metabolic disorders and cancer. A key focus of my work is the epigenetic control of metabolism in the liver, where I study how hyperacetylated histones drive lipid synthesis and metabolic dysregulation in conditions like insulin resistance, fatty liver disease, and hepatocellular carcinoma. Using cell culture techniques and patient biopsy samples and advanced mass spectrometry techniques, we aim to identify novel epigenetic biomarkers with potential clinical applications.

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